基本情報

鈴木 智大(スズキ トモヒロ)

役 職 准教授
学 位 博士(農学)
性 別 男性
生 年 1981年
研究室電話番号
研究室FAX番号
メールアドレス suzukit※cc.utsunomiya-u.ac.jp

(※を@にして送信してください)

研究室サイト http://c-bio.mine.utsunomiya-u.ac.jp/suzuki/

所属組織学歴本学以外の主な職歴教育活動研究活動組織・運営情報

所属組織

・学内共同教育研究施設等 バイオサイエンス教育研究センター

学歴

博士(農学)

本学以外の主な職歴

教育活動

専門分野

主な授業科目

分子生命科学I(分担)

授業内容

研究活動

専門分野

生物化学・天然物化学・生命情報学

専門分野(科研費分類)

木質科学

専門分野(Read分類)

学術論文

1. Hirayama, Y., Yamagishi, K., Suzuki, T., Kawagishi, H., Kita, M. and Kigoshi, H. Analysis of the aplyronine A-induced protein-protein interaction between actin and tubulin by surface plasmon resonance. Bioorganic Medicinal Chemistry, in press.
2. Yamamoto, T., Tsunematsu, Y., Hara, K., Suzuki, T., Kawagishi, H., Noguchi, H., Hashimoto, H., Tang, Y., Hotta, K. and Watanabe, K. Oxidative Trans-to-Cis Isomerization of Olefin in Polyketide Biosynthesis. Angewandte Chemie International Edition, in press.
3. Muraguchi, Y., Kushimoto, K., Ohtsubo, Y., Suzuki, T., Dohra, H., Kimbara, K. and Shintani, M. Complete genome sequence of the Algoriphagus sp. M8-2 isolated from brackish lake. Genome Announcements, in press.
4. Hirata, H., Kashihara, M., Horiike, T., Suzuki, T., Dohra, H., Netsu, O., and Tsuyumu, S. Genome sequence of Pectobacterium carotovorum phage PPWS1 isolated from Japanese horseradish [Eutrema japonicum (Miq.) Koidz] showing soft-rot symptom. Genome Announcements, in press.
5. Matsuzaki, M., Mizushima, S., Hiyama, G., Hirohashi, N., Shiba, K., Inaba, K., Suzuki, T., Dohra, H., Ohnishi, T., Sato, Y., Kohsaka, T., Ichikawa, Y., Atsumi, Y., Yoshimura, T., and Sasanami T*. Lactic acid is a sperm motility inactivation factor in the sperm storage tubules. Scientific Reports, 5, 17643 (2015).
6. †Choi, JH., †Suzuki, T., Okumura, H., Nagai, K., Hirai, H. and Kawagishi, H*. Thapsigargin-induced ER stress suppressive compounds from the mushroom Mycoleptodonoides aitchisonii. Tetrahedron Letters, 56, 5561-5563 (2015).
7. Suzuki, T., Takeshima, Y., Mikamoto, T., Saeki, JD., Kato, T., Park, EY., Kawagishi, H*., Dohra, H*. Genome sequence of a novel iflavirus from mRNA sequencing of the pupa of Bombyx mori inoculated with Cordyceps militaris. Genome Announcements, 3, e01039-15(2015).
8. Hwang, IW., Makishima, Y., Suzuki, T., Kato, T., Park, S., Terzic, A., Chung, SK. and Park EY*. Phosphorylation of Ser-204 and Tyr-405 in human malonyl-CoA decarboxylase expressed in silkworm Bombyx mori regulates catalytic decarboxylase activity. Applied Microbiology and Biotechnology, 99, 8977-8986 (2015).
9. Suzuki, T., Abe, T., Umehara, K., Choi, JH., Hirai, H., Dohra, H., and Kawagishi H*. Purification and characterization of a lectin from the mushroom Hypsizigus marmoreus. Mycoscience, 56, 359-393(2015).
10. Kobori, H., Sekiya, A., Suzuki, T., Choi, JH., Hirai, H. and Kawagishi, H*. Bioactive sesquiterpene aryl esters from the culture broth of Armillaria Journal of Natural Products, 78, 163-167(2015)
11. Wu, J., Tokunaga, T., Kondo, M., Ishigami, K., Tokuyama,S., Suzuki, T., Choi, JH., Hirai, H. and Kawagishi, H*. Erinaceolactones A to C, from the culture broth of Hericium erinaceus. Journal of Natural Products, 78, 155-158(2015)
12. †Yamamoto, N., †Suzuki, T., †Kobayashi, M., Dohra, H., Sasaki, Y., Hirai, H., Yokoyama, K., Kawagishi H*. and Yano, K*. A-WINGS: an integrated genome database for Pleurocybella porrigens (Angel's wing oyster mushroom, Sugihiratake) BMC Research Notes, 7, 866(2014)
13. Dohra, H., Tanaka, K., Suzuki, T., Fujishima, M. and Suzuki, H*. Draft genome sequences of three Holospora species (Holospora obtusa, Holospora undulata, and Holospora elegans), endonuclear symbiotic bacteria of the ciliate Paramecium caudatum, FEMS Letters, 359, 16-18(2014).
14. †Choi, JH., †Suzuki, T., Okumura, H., Noguchi, K., Kondo, M., Nagai, K., Hirai, H. and Kawagishi, H*. Endoplasmic reticulum stress suppressive compounds from the edible mushroom Mycoleptodonoides aitchisonii, Journal of Natural Products, 77, 1729-1733(2014)
15. †Choi, JH., †Suzuki, T., Kawaguchi, Y., Yamashita, K., Morita, A., Masuda,K., Yazawa, K., Hirai, H. and Kawagishi, H*. Makomotines A to D from Makomotake, Zizania latifolia infected with Ustilago esculenta, Tetrahedron Letters, 55, 3596-3599(2014)
16. Ikeuchi, K., Fujii, R., Sugiyama, S., Asakawa, T., Inai, M., Hamashima, Y., Choi, J.-H., Suzuki, T., Kawagishi, H*. and Kan, T*. Practical synthesis of natural plant-growth regulator 2-azahypoxanthine, its derivatives, and biotin-labeled probes, Organic and Biomolecular Chemistry, 12, 3813-3815(2014)
17. Ali, MP, Yoshimatsu, K., Suzuki, T., Kato, T. and Park EY*. Expression and purification of cyto-insectotoxin (Cit1a) using silkworm larvae targeting for an antimicrobial therapeutic agent. Applied Microbiology and Biotechnology, 98, 6973-6982(2014)
18. Suzuki, T., Dohra, H., Omae, S., Takeshima, Y., Choi, JH., Hirai, H. and Kawagishi, H*. Heterologous expression of a lectin from Pleurocybella porrigens (PPL) in Phanerochaete sordida YK-624. Journal of Microbiological Methods, 100, 70-76(2014)
19. Qiu, W., Kobori, H., Suzuki, T., Choi, JH., Deo, VK., Hirai, H. and Kawagishi, H*. A new compound from the mushroom Tricholoma flavovirens. Bioscience, Biotechnology, and Biochemistry, 78, 755-757(2014)
20. Choi, JH., Ohnishi, T., Yamakawa, Y., Takeda, S., Sekiguchi, S., Maruyama, W., Yamashita, K., Suzuki, T., Morita, A., Ikka T., Motohashi, R., Kiriiwa, Y., Tobina, H., Asai, T., Tokuyama, S., Hirai, H., Yasuda, N., Noguchi, K., Asakawa, T., Sugiyama, S., Kan, T. and Kawagishi, H*. The source of "fairy rings": 2-azahypoxanthine and its metabolite found in a novel purine metabolic pathway in plants. Angewandte Chemie International Edition, 53, 1552-1555(2014)
21. Wu J., Suzuki, T., Choi J.-H., Yasuda N., Noguchi K., Hirai H. and Kawagishi H*. An unusual sterol from the mushroom Stropharia rugosoannulata. Tetrahedron Letters, 54, 4900-4902(2013)
22. Dohra, H., Suzuki, H., Suzuki, T., Tanaka, K., Fujishima, M*. Draft genome Sequence of Holospora undulate strain HU1, a micronucleus-specific symbiont of the ciliate Paramecium caudatum. Genome Announcements, 1, e00664-13(2013)
23. Kobori, H., Sekiya, A., Yasuda, N., Noguchi, K., Suzuki, T., Choi, JH., Hirai, H. and Kawagishi, H*. Armillariols A to C from the culture broth of Armillaria sp. Tetrahedron Letters, 54, 5481-5473(2013)
24. Choi, JH., Yoshida, M., Suzuki, T., Harada, E., Kawade, M., Yazawa, K., Nishimoto, S., Hirai, H. and Kawagishi, H*. A novel sphingosine with osteoclast-forming suppressing activity, from the edible mushroom Grifola gargal. Tetrahedron, 69, 8609-8611(2013)
25. Hirai, H*., Misumi, K., Suzuki, T. and Kawagishi, H. Improvement of manganese peroxidase production by the hyper lignin-degrading fungus Phanerochaete sordida YK-624 by recombinant expression of the 5-aminolevulinic acid synthase gene. Current Microbiology, 67, 708-711(2013)
26. †Suzuki, T., †Igarashi, K., Dohra, H., Someya, T., Takano, T., Harada, K., Omae, S., Hirai, H., Yano, K*. and Kawagishi, H*. A new omics data resource of Pleurocybella porrigens for gene discovery. Plos One, 8, e69681(2013)
27. Wu, J., Kobori, H., Kawaide, M., Suzuki, T., Choi, JH., Yasuda, N., Noguchi, K., Matsumoto, T., Hirai, H. and Kawagishi, H*. Isolation of bioactive steroids from the mushroom Stropharia rugosoannulata and absolute configuration of strophasterol B. Bioscience, Biotechnology, and Biochemistry, 77, 1779-1781(2013)
28. †Suzuki, T., †Choi, JH., Kawaguchi, T., Yamashita, K., Morita, A., Hirai, H., Nagai, K., Hirose, T., Omura, S., Sunazuka, T. and Kawagishi, H*. Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta. Bioorganic & Medicinal Chemistry Letters, 22, 4246-4248(2012)
29. Suzuki, T., Sugiyama, K., Hirai, H., Ito, H., Morita, T., Dohra, H., Murata, T., Usui, T., Tateno, H., Hirabayashi, J., Kobayashi, Y. and Kawagishi, H*. Mannose α1-6-specific lectin from the mushroom Hygrophorus russula. Glycobiology, 22, 616-629(2012)
30. Imai, Y., Hirono, S., Matsuba, H., Suzuki, T., Kobayashi, Y., Kawagishi, H., Takahashi, D. and Toshima, K*. Degradation of target oligosaccharides by anthraquinone-lectin hybrids with light switching. Chemistry-An Asian Journal, 7, 97-104(2012)
31. Suzuki, T., Umehara, K., Tashiro, A., Kobayashi, Y., Dohra, H., Hirai, H. and Kawagishi, H*. An antifungal protein from the culinary-medicinal beech mushroom, Hypsizygus marmoreus (Peck) Bigel. (Agaricomycetideae). International Journal of Medicinal Mushrooms, 13, 27-31(2011)
32. Wakimoto, T., Asakawa, T., Akahoshi, S., Suzuki, T., Nagai, K., Kawagishi, H*. and Kan, T*. Proof of the existence of an unstable amino acid: Pleurocybellaziridine in Pleurocybella porrigens. Angewandte Chemie International Edition, 50, 1168-1170 (2011)
33. Kawaguchi, T., Suzuki, T., Kobayashi, Y., Kodani, S., Hirai, H., Nagai, K. and Kawagishi, H*. Unusual amino acid derivatives from the mushroom Pleurocybella porrigens. Tetrahedron 66, 504-507(2010)
34. Ogata, M., Kameshima, Y., Hattori, T., Michishita, K., Suzuki, T., Kawagishi, H., Totani, K. and Usui, T*. Lactosylamidine-based affinity purification for cellulolytic enzymes EG I and CBH I from Hypocrea jecorina and their properties. Carbohydrate Research, 345, 2623-2629(2010)
35. Suzuki, T., Amano, Y., Fujita, M., Kobayashi, Y., Dohra, H., Hirai, H., Murata, T., Usui, T., Morita, T. and Kawagishi, H*. Purification, characterization and cDNA cloning of a lectin from the mushroom Pleurocybella porrigens. Bioscience, Biotechnology, and Biochemistry, 73, 702-709(2009)
36. Inagaki, N., Shibata, T., Itoh, T., Suzuki, T., Tanaka, H., Nakamura, T., Akiyama, Y., Kawagishi, H. and Nagai, H*. Inhibition of IgE-dependent mouse triphasic cutaneous reaction by a boiling water fraction separated from mycelium of Phellinus linteus. Evidence-based Complementary and Alternative Medicine, 2, 369?374 (2005)

著書

特許・実用新案・意匠

研究資金

1. 科研費 若手研究(B), スギヒラタケの毒性解明と特異な基質開裂特性を有する新規酵素の創出, 平成26年-平成27年度, 代表
2. 科研費 基盤研究(B), 担子菌類-植物共生メカニズムの解明及び劣悪環境下における食糧生産への応用, 平成26-平成27年度, 分担
3. 第29回 ノバルティス研究奨励金, スギヒラタケ食中毒事件の化学的解明、平成28年度、代表
4. 第13回コスモバイオ公開講座応援団, バイオテクノロジー体験講座, 平成28年度、代表

受賞

第52回天然有機化合物討論会奨励賞(平成22年9月)
第5回新規素材探索研究会奨励賞(平成18年6月)

その他の研究実績

所属学会

天然有機化合物討論会、日本農芸化学会、日本生化学会

組織・運営情報

全学・部局委員会等

学外活動